Primary Identifier | MGI:1857977 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd14 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 272 bp genomic segment containing exon 1 and part of exon 2, including the initiation codon, was replaced with a neomycin resistance gene. Flow cytometry experiments on peritoneal macrophages derived from homozygous mice confirmed that no stable protein was made from this allele. |