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Allele : Tlr4<lps-del> toll-like receptor 4; defective lipopolysaccharide response, deletion
Primary Identifier  MGI:1860755 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Tlr4
Inheritance Mode  Recessive Strain of Origin  C57BL/10ScN
Is Recombinase  false Is Wild Type  false
description  C57BL/10ScN, C57BL/10ScNJ, and C57BL10/ScCr mice carry this allele.
molecularNote  This allele has been characterized by lack of mRNA owing to a deletion of the locus. 74723bp of genomic DNA sequence have been removed, encompassing only the Tlr4 gene.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • TLR4-KO,
  • TLR4<lps->,
  • Tlr4<->,
  • Tlr4<->,
  • TLR4<lps->,
  • TLR4-KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

0 Driven By

364 Publication categories





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