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Allele : Gabrd<tm1Geh> gamma-aminobutyric acid (GABA) A receptor, subunit delta; targeted mutation 1, Gregg E Homanics

Primary Identifier  MGI:1861926 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gabrd
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Insertion of a MC1-neomycin resistance cassette into exon 4 disrupted the gene. Northern blot analysis of cerebellar total RNA from homozygous mutant adult mice detected moderate levels of a novel 2.3kb transcript but not the 1.9kb wild-type transcript. Western blot analysis of cerebellar membranes did not detect the wild-type protein in homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • delta<0>,
  • delta-,
  • delta-,
  • delta<0>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

64 Publication categories