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Allele : Tcf7<tm2Cle> transcription factor 7, T cell specific; targeted mutation 2, Hans Clevers

Primary Identifier  MGI:1926299 Allele Type  Targeted
Attribute String  Hypomorph Gene  Tcf7
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A 350-bp fragment encoding part of intron IV and exon V was replaced with a neomycin cassette. A novel mRNA was detected in homozgyote thymocytes at 15% of the wild-type mRNA level. This mutant mRNA contains a splice variant of exon 4 to exon 6. This allele is considered a hypomorph.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Tcf<deltaV>,
  • Tcf<deltaV>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories