Primary Identifier | MGI:1930367 | Allele Type | Radiation induced |
Gene | Bmp5 | Inheritance Mode | Recessive |
Strain of Origin | (C3H/Rl x 101/Rl)F1 | Is Recombinase | false |
Is Wild Type | false |
description | This mutation was originally generated by treatment of F1 mice with 100 + 500 rads of fractional acute X radiation. |
molecularNote | Evidence of DNA rearrangement at this locus as noted by altered restriction fragment polymorphisms. The Bmp5 open reading frame could not be amplified from strain 38DSD. 38DSD is a 30.7 Mb inversion with breakpoints in intron 6 of Bmp5 and intron 1 of Tmprss4. The Bmp5 breakpoint is between chr9:75,896,515-75,896,518 (4 bp duplicated). The Tmprss4 breakpoint is between chr9:45,190,204-45,190,206 (1 bp deletion). |