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Allele : Cdkn2b<tm1Bbd> cyclin dependent kinase inhibitor 2B; targeted mutation 1, Mariano Barbacid

Primary Identifier  MGI:1933760 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdkn2b
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 2, encoding amino acids 44-130, was replaced by a neomycin cassette. No protein was detectable in Western blots of immunoprecipitates of MEF lysates derived from homozygous mutant embryos.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • p15<INK4b>-,
  • p15<INK4b>-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

13 Publication categories