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Allele : Per2<tm1Brd> period circadian clock 2; targeted mutation 1, Allan Bradley

Primary Identifier  MGI:1934020 Allele Type  Targeted
Attribute String  Null/knockout Gene  Per2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Two exons containing the most conserved region of the gene were replaced with PGK-neo cassette, resulting in the deletion of the PAC subdomain and half of the PAS B domain. RT-PCR and sequence analysis of mutant animals detected a mutant transcript with a predicted protein containing an 87 amino acid deletion.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • mPer2<Brdm1>,
  • Per2<Brdm1>,
  • mPer2<Brdm1>,
  • Per2<Brdm1>,
  • mPer2<m>,
  • mPer2<m>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

105 Publication categories