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Allele : Grb2<tm1Paw> growth factor receptor bound protein 2; targeted mutation 1, Tony Pawson

Primary Identifier  MGI:2152451 Allele Type  Targeted
Attribute String  Null/knockout Gene  Grb2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing exons 2 and 3 was replaced with a vector containing a neomycin selection cassette by homologous recombination. Immunoprecipitation and western blotting experiments on cell lysates derived from homozygous mice confirmed that no detectable protein was made from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • deltaGrb2,
  • deltaGrb2,
  • Grb2-,
  • Grb2-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

17 Publication categories