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Allele : Gna13<tm1Soff> guanine nucleotide binding protein, alpha 13; targeted mutation 1, Stefan Offermanns

Primary Identifier	MGI:2151775	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Gna13
Transmission	Germline	Strain of Origin	129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A genomic fragment containing the first exon was replaced with a neomycin cassette. RT-PCR analysis did not detect a transcript produced from this allele in homozygous mice.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Galpha13<->,
Galpha13<->

earliestPublication:
Offermanns S, et al. (1997) Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science 275(5299):533-6

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

12 Publication categories

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