Primary Identifier | MGI:2153198 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Otx1 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette was inserted into the exon that encodes the homeobox sequences of the protein. A mutant transcript consisting of neomycin sequences fused to 3' gene sequences was produced, but stop codons in the neomycin gene are predicted to prevent expression of protien from this allele. |