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Allele : Fgfr1<tm3Jrt> fibroblast growth factor receptor 1; targeted mutation 3, Janet Rossant

Primary Identifier  MGI:2153345 Allele Type  Targeted
Attribute String  Hypomorph, Modified isoform(s) Gene  Fgfr1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP flanked neomycin cassette was inserted into intron 7, and a point mutation was introduced in IIIc that introduced an in frame stop codon to specifically disrupt expression of the IIIc isoform of the protein. This is a hypomorphic allele.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • IIIcn,
  • IIIcn
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories