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Allele : Epha4<tm3Kln> Eph receptor A4; targeted mutation 3, Rudiger Klein

Primary Identifier  MGI:2156481 Allele Type  Targeted
Attribute String  Hypomorph, Inserted expressed sequence Gene  Epha4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA encoding a mutant protein with a substitution of phenylalanines for tyrosines 596 and 602 was fused in frame into exon 3 of the gene followed by a poly (A) site and a loxP flanked neomycin selection cassette. Western blot analysis confirmed the expression of the fusion protein in homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • ephA4<2F>,
  • ephA4<2F>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories