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Allele : Atp4a<tm1Ges> ATPase, H+/K+ exchanging, gastric, alpha polypeptide; targeted mutation 1, Gary E Shull

Primary Identifier  MGI:2158246 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atp4a
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A part of exon 8 encoding amino acids 360-390 was replaced with a neomycin selection cassette. Northern blot analysis demonstrated that no detectable full length transcript was produced from this allele in stomach of homozygous mice, although trace levels of a shorter 1 kb transcript was detected. Immunocytochemistry experiments on stomach tissue of homozygous mice demonstrated that no detectable protein was present.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • H/Kalpha<->,
  • H/Kalpha<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

24 Publication categories