Primary Identifier | MGI:2158690 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ikzf1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted using neomycin resistance cassette. The vector replaced a major part of the coding region of exon 7, predicted to affect the C- terminal zinc finger involved in activation, dimerization and other protein interactions. Protein was not detected in homozygous mutant animals by immunohistochemical or Western analysis. |