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Allele : S1pr1<tm1Rlp> sphingosine-1-phosphate receptor 1; targeted mutation 1, Richard L Proia

Primary Identifier  MGI:2158346 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  S1pr1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  An IRES-lacZ reporter gene and neomycin selection cassette was inserted after codon 42 of the coding region of the gene. RT-PCR analysis demonstrated that the endogenous transcript was not detectable in homozygous embryos. A beta-galactosidase protein was expressed from this allele under the control of the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • S1pr1<->,
  • Slp1<-LacZ>,
  • Edg1<LacZ>,
  • S1P1<Ko>,
  • Edg1<LacZ>,
  • S1P1<->,
  • S1P1<->,
  • S1P1<Ko>,
  • Slp1<-LacZ>,
  • S1pr1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

34 Publication categories