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Allele : Dmc1<tm1Jcs> DNA meiotic recombinase 1; targeted mutation 1, John C Schimenti

Primary Identifier  MGI:2176331 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dmc1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing sequences encoding the conserved DNA binding motif required for protein activity. RT-PCR analysis on RNA derived from testis of homozygous males demonstrated that no detectable transcript was produced from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Dmc1<->,
  • Dmc1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

44 Publication categories