|  Help  |  About  |  Contact Us

Allele : Spo11<tm1Mjn> SPO11 initiator of meiotic double stranded breaks; targeted mutation 1, Maria Jasin

Primary Identifier  MGI:2178805 Allele Type  Targeted
Attribute String  Null/knockout Gene  Spo11
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 4-6 of this gene were replaced with a neomycin resistance cassette via homologous recombination thus deleting the putative catalytic tyrosine in exon 5. Northern blot assay failed to detect gene transcripts in testes of homozygous mutant males.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Spo11-,
  • Spo<tm1M>,
  • Spo11<tm1Sky>,
  • Spo11<tm1Sky>,
  • Spo11-,
  • Spo<tm1M>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

75 Publication categories