| Primary Identifier | MGI:2179128 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ppm1d |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 4 and 5 were replaced with a PGK-puro cassette via homologous recombination resulting in protein truncation. Northern blot analysis of tissues from homozygous mutant animals did not detect gene transcript although a transcript with deleted exons 4 and 5, presumed to be unstable, was detected by RT-PCR. Western blot of irradiated testes from homozygous mutants did not detect protein product. |
