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Allele : Adh1<tm2Gdu> alcohol dehydrogenase 1 (class I); targeted mutation 2, Gregg Duester

Primary Identifier  MGI:2180099 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adh1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
description  A modified R1 ES cell line dervived from (129X1/SvJ x 129S1/Sv)F1-Kitl+ containing a targeted Adh3 (class III) locus was used.
molecularNote  Exons 7 through 9 and the polyadenylation signal were replaced with a PGK-hygro gene downstream of exon 6. This construct was developed by altering a previously described construct, tm1Due, containing a neomycin selection gene, for use in the generation of a double knockout.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Adh1<->,
  • Adh1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories