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Allele : Nfkb2<tm2Brv> nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; targeted mutation 2, Rodrigo Bravo

Primary Identifier  MGI:2180306 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nfkb2
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was disrupted by the replacement of exon 4 with a neomycin resistance cassette via homologous recombination. Radioimmunoprecipitation assay and electrophoretic mobility shift assay (EMSA) did not detect any protein product in thymus and spleen extracts from homozygous mutant animals.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • p100,
  • p52,
  • NF-kappaB2 KO,
  • NF-kappaB2 KO,
  • Nfkappab2-,
  • NF-kappaB2<->,
  • p52,
  • Nfkappab2-,
  • p100,
  • NF-kappaB2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

33 Publication categories