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Allele : Il5ra<tm1Ktk> interleukin 5 receptor, alpha; targeted mutation 1, Kiyoshi Takatsu

Primary Identifier  MGI:2180501 Allele Type  Targeted
Attribute String  Null/knockout Gene  Il5ra
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A stop codon was introduced into exon 5 and a neo cassette was inserted into exon 6 via homologous recombination. The neo insertion disrupts 4 cysteine residues that are conserved within the cytokine receptor family. Absence of gene expression was verified by flow cytometry analysis of resting peritoneal cells from homozygous mutant animals.
  • mutations:
  • Insertion
  • synonyms:
  • IL-5Ralpha<->,
  • IL-5Ralpha<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

16 Publication categories