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Allele : Cd19<tm1Tft> CD19 antigen; targeted mutation 1, Thomas F Tedder

Primary Identifier  MGI:2180685 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd19
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 5 encoding the transmembrane domain and 7 of the 9 exons encoding cytoplamic domains were replaced with a neomycin cassette. In addition, the inserted neomycin gene introduced a stop codon. Immunohistochemical staining showed a lack of protein expression in the spleens of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CD19-,
  • CD19-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

38 Publication categories