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Allele : Cry2<tm1Jhjh> cryptochrome circadian regulator 2; targeted mutation 1, Jan H J Hoeijmakers

Primary Identifier	MGI:2181206	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cry2
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

A neomycin selection cassette replaced coding sequence corresponding to base pairs 397 through 810 in the cDNA sequence. RT-PCR analysis indicated a lack of transcript in homozygous mutant mice.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
cry2-,
cry2-,
mCry2-,
mCry2-

earliestPublication:
van der Horst GT, et al. (1999) Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms [see comments]. Nature 398(6728):627-30

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

71 Publication categories

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