| Primary Identifier | MGI:2181608 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | P2rx1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 1, encoding the first 45 amino acids, and surrounding intronic sequence were replaced using a vector containing lacZ and neo. Transcript was undetected by RT-PCR analysis of homozygous mutant mice. Western blot analysis, using an antibody raised against the carboxy-terminal, showed an absence of protein in homozygous mutant mice. A lack of immunoreactivity was observed in sections of the vas deferens obtained from homozygous mutant mice. |
