Primary Identifier | MGI:2182456 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nppc |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1 and 2, which contain the entire coding sequence, were replaced with a neomycin resistance gene via homologous recombination. RNase protection assays demonstrated the absence of gene expression in various tissues from homozygous mutant animals. |