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Allele : Pten<tm2Mak> phosphatase and tensin homolog; targeted mutation 2, Tak W Mak

Primary Identifier  MGI:2182005 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Pten
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  One loxP site was inserted in intron 3 and a floxed hygromycin selection cassette was inserted in intron 5. The hygromycin selection cassette was removed in ES cells by transient Cre expression, leaving exons 4 and 5 flanked by loxP sites in the final allele.
  • mutations:
  • Insertion
  • synonyms:
  • Pten<loxP>,
  • Pten<flox>,
  • PTEN<Co>,
  • Pten<L>,
  • PTEN<Co>,
  • Pten<fl>,
  • Pten<L>,
  • Pten<flox>,
  • Pten<f>,
  • Pten<f>,
  • Pten<loxP>,
  • Pten<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

258 Publication categories