| Primary Identifier | MGI:2182113 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Npy |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2, which encodes the signal peptide and 35 amino acids, was replaced by a lacZ-neo fusion gene. The expression pattern of the beta-galactosidase was shown to resemble that of the endogenous gene via comparisons of X-gal staining and previous in situ hybridization studies. RT-PCR analysis of brain tissue showed an absence of transcript in homozygous mutant mice. |
