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Allele : Shc1<tm1Ravi> src homology 2 domain-containing transforming protein C1; targeted mutation 1, Kodi S Ravichandran

Primary Identifier  MGI:2384183 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Shc1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1 and 2, encoding the transcriptional start site and the amino terminals of the three known isoforms, were flanked by a single upstream loxP site and a floxed neo cassette inserted into intron 2. Transient transfection of ES cells resulted in the excision of the floxed neo cassette, leaving the first two exons surrounded by single loxP sites.
  • mutations:
  • Insertion
  • synonyms:
  • Shc<fl>,
  • Shc<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele