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Allele : Ccl11<tm1Mer> C-C motif chemokine ligand 11; targeted mutation 1, Marc E Rothenberg

Primary Identifier  MGI:2384435 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ccl11
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  All of exon 2 and the majority of exon 3 were replaced by a neomycin selection cassette. In addition to containing the 3' UTR, the deleted region encoded most of the mature protein. Transcript was undetected in homozygous mutant mice via Northern blot analysis of skin and lung RNA (the latter of which was isolated from mice treated with and subsequently challenged with OVA).
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • eotaxin-1,
  • eotaxin-,
  • Eot<->,
  • eotaxin-1,
  • eotaxin-,
  • Eot<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

31 Publication categories