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Allele : Nkx2-3<tm1Hha> NK2 homeobox 3; targeted mutation 1, Hans-Henning Arnold

Primary Identifier  MGI:2386680 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nkx2-3
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  The entire coding region of the gene was deleted and replaced with a PGK-neo cassette via homologous recombination. Northern blot analysis of RNA from the duodenum, jejunum, and colon of homozygous mutant animals did not detect gene expression. In situ hybridization of E9.5 homozygous mutant embryos also failed to detect gene transcripts.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nkx2.6<->,
  • Nkx2.6<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

12 Publication categories