| Primary Identifier | MGI:2386598 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Fmn1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| description | Homozygous mutant mice have normal limbs, but display variably penetrant renal aplasia characteristic of other limb deformity mutant alleles (J:50647). |
| molecularNote | Exon 4 was replaced by a PGK-neo cassette inserted by homologous recombination. Circular transcripts were undetected by RT-PCR analysis of brain and kidney samples obtained from homozygous mutant mice. Ribonuclease protection assays showed that transcripts lacking the targeted exon were present at normal levels in homozygous mutant mice. Corresponding results were obtained by Western blot analysis. |
