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Allele : Gvhd4<DBA/2J> graft-versus host disease 4; DBA/2J
Primary Identifier  MGI:2386611 Allele Type  QTL
Gene  Gvhd4 Inheritance Mode  Not Specified
Strain of Origin  DBA/2J Is Recombinase  false
Is Wild Type  false
description  Donors homozygous for DBA/2-derived alleles at both Gvhd4 and Gvhd5 appear to induce stronger autoantibody response in recipient animals.
molecularNote  In donor animals, this allele confers increased renal pathology and increased anti-ssDNA autoantibody production in recipient animals compared to C57BL/10.
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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