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Allele : Nppb<tm1Yog> natriuretic peptide type B; targeted mutation 1, Yoshihiro Ogawa

Primary Identifier	MGI:2386215	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Nppb
Transmission	Germline	Strain of Origin	129/Sv
Is Recombinase	false	Is Wild Type	false

molecularNote

The gene was disrupted by replacement of exons 1-2 with a neomycin resistance cassette via homologous recombination. Gene transcripts and protein product were not detectable in the hearts of homozygous mutant animals.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
BNP<->,
Nppb<->,
Nppb<->,
BNP<->

earliestPublication:
Tamura N, et al. (2000) Cardiac fibrosis in mice lacking brain natriuretic peptide. Proc Natl Acad Sci U S A 97(8):4239-44

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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