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Allele : Prox1<tm1Gco> prospero homeobox 1; targeted mutation 1, Guillermo Oliver

Primary Identifier  MGI:2386336 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Prox1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
description 

In J:53431, the original chimeric mice were crossed to four different genetic backgrounds. In three (unspecified) backgrounds mortality was 100% penetrant, whereas crosses to the NMRI background produced some surviving heterozygotes, which were used to generate homozygous embryos.

molecularNote  A cassette containing lacZ and neo was fused in frame at the codon 224. Expression of beta-galactosidase was driven by the endogenous promoter.
  • mutations:
  • Insertion
  • synonyms:
  • Prox<LacZ>,
  • Prox<LacZ>,
  • Prox1-,
  • Prox1-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

27 Publication categories

Trail: Allele