Primary Identifier | MGI:2387772 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Thy1-Serpine2)2Dmn |
Is Recombinase | false | Is Wild Type | false |
description | Transgenic line T2 expressed rat Serpine2 mRNA and protein at high levels in the brain (2-fold higher compared to transgenic line T1). |
molecularNote | The transgene consists of mouse Thy1 regulatory sequences fused to rat Serpine2 cDNA. The mouse Thy1 promoter was used to drive expression of the transgene in the CNS. Transgene expression was detected in the brain, and a low level of transgene expression was detected in the lungs. |