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Allele : Hmox2<tm1Poss> heme oxygenase 2; targeted mutation 1, Kenneth D Poss

Primary Identifier  MGI:2388325 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hmox2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Approximately 80% of the coding region was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region included the putative membrane spanning region. Transcript was undetected in homozygous mutant mice by Northern blot analysis of brain tissue. An assay based on bilirubin production indicated complete functional ablation in homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • HO-2<->,
  • HO2<->,
  • HO2<->,
  • HO-2<->,
  • HO-2<delta>,
  • HO-2<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

56 Publication categories