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Allele : Irf4<tm1Mak> interferon regulatory factor 4; targeted mutation 1, Tak Mak

Primary Identifier	MGI:2387941	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Irf4
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 2 and 3 were replaced by a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of concanavalin A activated lymph nodes obtained from homozygous mutant mice.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
IRF-4-,
IRF4-,
IRF4-,
IRF-4-

earliestPublication:
Mittrucker HW, et al. (1997) Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275(5299):540-3

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

84 Publication categories

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