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Allele : Hoxa11<tm2(Hoxa13)Ssp> homeobox A11; targeted mutation 2, S Steven Potter

Primary Identifier  MGI:2388356 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hoxa11
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  ES cell line = R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+) or E14.1 (129P2/OlaHsd).
molecularNote  The exon 2 homeodomain of Hoxa11 as precisely replaced with the homeodomain of Hoxa13, and a floxed neo cassette was inserted into a region 3' of the gene for positive selection. Interestingly, the 3' neo insert results in disruption of the gene.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories