| Primary Identifier | MGI:2388123 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Stam |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of exons 3 and 4 encoding amino acids 44-99 with a neomycin resistance cassette. RT-PCR analysis of splenocyte RNA from homozygous mutant animals detected a mutant transcript with a frameshift and nonsense codon in exon 5. Western blot analysis of neocortex lysates and immunoprecipitation immunoblot of activated T cells from homozygous mutant animals did not detect a protein product. |
