| Primary Identifier | MGI:2388141 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Plcg1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Coding sequence was disrupted by the insertion of a neomycin selection cassette. While normal protein was undetected by Western blot analysis of MEFs derived from homozygous mutant mice, low levels of a shortened peptide containing both amino and carboxy termini was. Calcium mobilization assays showed that the mutant protein responded to serum, but not epidermal growth factor. |
