| Primary Identifier | MGI:2388143 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mat1a |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| description | Expression of Mat2a mRNA was induced 3-fold in homozygous mutant animals. Expression of Afp mRNA was also increased in homozygous mutants. |
| molecularNote | The gene was disrupted by insertion of a PGK-neo cassette into exon 3 via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by Northern and Western blot of liver RNA and proteins. |
