| Primary Identifier | MGI:2389509 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ak1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 3 through 5, encoding the ATP binding site, were replaced with a hygromycin selection cassette inserted by homologous recombination. Transcript was undetected by Northern blot analysis of skeletal muscle, heart, and brain tissue obtained from homozygous mutant mice. Zymogram analysis of various tissues confirmed the absence of functional protein. |
