| Primary Identifier | MGI:2429688 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Chl1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene was disrupted by replacement of exon 1 (and 4 kb of intron 1) with a PGK-neo cassette via homologous recombination, thus deleting the ribosomal binding site, translation initiation codon, and signal sequence. Absence of gene expression in homozygous mutant animals was verified by Western blot analysis of brain protein extracts. |
