| Primary Identifier | MGI:2445418 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sgk1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A region containing exons 4 through 11 was deleted by in vitro cre mediated recombination of a single loxP site inserted in intron 3 and a floxed neo cassette downstream of exon 11. The deleted region encoded the entire kinase domain. A shortened transcript, corresponding to a 0.9 kb deletion, was identified in homozygous mutant mice by Northern blot analysis. |