Primary Identifier | MGI:2445432 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Procr |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = AB2. |
molecularNote | Exon 1 was flanked by loxP sites and subsequently excised via in vitro cre mediated recombination. The resultant germline allele contained a single loxP site in place of exon 1, which included the 5' untranslated region and encoded the start codon, signal peptide, and part of the extracellular domain. RT-PCR indicated an absence of transcript in homozygous mutant embryos. |