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Allele : Tg(Lck-Hhex)1Hro transgene insertion 1, Robert Hromas

Primary Identifier  MGI:2448671 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Lck-Hhex)1Hro
Strain of Origin  C3HeB/FeJ Is Recombinase  false
Is Wild Type  false
description  Six transgenic founders were created. Two transgenic animals with the highest transgene copy numbers died at 16 months of age and did not breed.
molecularNote  A full length Hhex cDNA sequence under regulatory control of a mouse Lck promoter was used for the transgene. Northern and Western blot analysis showed that transgene expression was exclusive to T lymphocytes.
  • mutations:
  • Insertion
  • synonyms:
  • Lck/Hex,
  • Lck/Hex
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories