Primary Identifier | MGI:2448671 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Lck-Hhex)1Hro |
Strain of Origin | C3HeB/FeJ | Is Recombinase | false |
Is Wild Type | false |
description | Six transgenic founders were created. Two transgenic animals with the highest transgene copy numbers died at 16 months of age and did not breed. |
molecularNote | A full length Hhex cDNA sequence under regulatory control of a mouse Lck promoter was used for the transgene. Northern and Western blot analysis showed that transgene expression was exclusive to T lymphocytes. |