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Allele : Gdf11<tm1Sjl> growth differentiation factor 11; targeted mutation 1, Sejin Lee

Primary Identifier	MGI:2449672	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Gdf11
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

Sequence encoding the majority of the carboxy terminal, which putatively contains the biologically active portion of the protein, was replaced with a neo cassette inserted by homologous recomibation.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Gdf11-,
Gdf11-

earliestPublication:
McPherron AC, et al. (1999) Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11. Nat Genet 22(3):260-4

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

22 Publication categories

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