Primary Identifier | MGI:2449673 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gdf11 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 was disrupted by the insertion of a PGK-neo cassette. The targeted allele putatively encodes a transcript lacking four of seven essential cysteine codons. RT-PCR analysis of total RNA obtained from olfactory turbinates indicated an absence of normal transcript in homozygous mutant embryos. |