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Allele : Gdf11<tm1Clf> growth differentiation factor 11; targeted mutation 1, Anne L Calof

Primary Identifier  MGI:2449673 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gdf11
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was disrupted by the insertion of a PGK-neo cassette. The targeted allele putatively encodes a transcript lacking four of seven essential cysteine codons. RT-PCR analysis of total RNA obtained from olfactory turbinates indicated an absence of normal transcript in homozygous mutant embryos.
  • mutations:
  • Insertion
  • synonyms:
  • Gdf11<tm2>,
  • Gdf11<tm2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories