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Allele : Brca2<tm2Hst> breast cancer 2, early onset; targeted mutation 2, Paul Hasty

Primary Identifier  MGI:2653914 Allele Type  Targeted
Attribute String  Null/knockout Gene  Brca2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Most of exon 26 and all of exon 27 (coding nt 9265 through 9984) were replaced by a neomycin selection cassette inserted by homologous recombination. The deleted region included the RAD51-interacting domain.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • brca2<lex2>,
  • brca2<lex2>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories