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Allele : Ddit3<tm1Dron> DNA-damage inducible transcript 3; targeted mutation 1, David Ron

Primary Identifier	MGI:2654034	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ddit3
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A PGK-neomycin resistance cassette replaced the coding region in parts of exons 3 and 4. Northern blot analyses did not detect transcript in MEFs from homozygous mutant E13.5 embryos.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
chop-,
chop-,
Chop null,
Chop null

earliestPublication:
Zinszner H, et al. (1998) CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12(7):982-95

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

40 Publication categories

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